French translation
anticorps
Category
Antibodies
Purification method
SerumSerum
Clonality
Polyclonal Antibodies
Gene name
Caspase 3, Active/Cleaved
Antigen
Caspase 3, Active/Cleaved
Clone
Not applicable to Polyclonal Antibodies
Form/Appearance
Supplied as a liquid, 0.05% sodium azide.
Gene synonims
CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1
Applications
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Concentration
Enquire us for detailed information on the concentration of this antibody
Reacts with
Canine, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Long name
Caspase 3, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
Synonim names
Anti -Caspase 3, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
Other names
caspase-3 preproprotein; Caspase-3; caspase-3; CASP-3; CPP-32; apopain; procaspase3; protein Yama; PARP cleavage protease; cysteine protease CPP32; SREBP cleavage activity 1; caspase 3, apoptosis-related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1
Specificity
Recognizes the large (~14-21kD) and small (~10kD) subunits of human active/cleaved caspase-3. Nuclear immunostaining of Caspase-3 is considered to be an indication of active/cleaved caspase-3. May also recognize the pro-form of caspase-3 (~32kD). Species Crossreactivity: canine, gerbil, mouse and rat ;This is an antibody designed to detect Caspase 3, Active/Cleaved
Storage, shipping and handling
The antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
