Other names
N/A
Gene synonims
N/A
French translation
anticorps
Category
Antibodies
Gene name
NFkB, p100/p52
Antigen
NFkB, p100/p52
Clonality
Polyclonal Antibodies
Clone
Not applicable to Polyclonal Antibodies
Reacts with
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Applications
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Concentration
Enquire us for detailed information on the concentration of this antibody
Purification method
Affinity PurifiedPurified by immunoThis antibody was purified via Affinity Chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Specificity
Recognizes endogenous levels of human NF-kB p100, p52 only when phosphorylated at serine 865. Species Crossreactivity: Mouse and rat. ;This is an antibody designed to detect NFkB, p100/p52
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Long name
NFkB, p100/p52, phosphorylated (Ser865) (Nuclear Factor NF-kappa-B p100 Subunit, DNA-binding Factor KBF2, H2TF1, Lymphocyte Translocation Chromosome 10 Protein, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 2, Oncogene Lyt-10, Lyt10,
Synonim names
Anti -NFkB, p100/p52, phosphorylated (Ser865) (Nuclear Factor NF-kappa-B p100 Subunit, DNA-binding Factor KBF2, H2TF1, Lymphocyte Translocation Chromosome 10 Protein, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 2, Oncogene Lyt-10, Lyt10,
Storage, shipping and handling
The antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial.
Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
