anti- ACVR1C antibody

Size

2X100μg

Catalog no#

FNab00130

Price

320 EUR

Uniprot ID

Q8NER5

Calculated MW

60 kDa

Form

liquid

French translation

anticorps

Tested Application

ELISA, WB, IHC

Specificity

Human, Mouse, Rat

Purification

Immunogen affinity purified

Immunogen

activin A receptor, type IC

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Synonyms

ACVR1C, Activin receptor type 1C, Activin receptor type IC, ACVRLK7, ALK 7

Image1

Immunohistochemistry of paraffin-embedded human stomach using FNab00130(ACVR1C antibody) at dilution of 1:100

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00130(ACVR1C antibody) at dilution of 1:1000

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).