anti- CD3 epsilon antibody

Size

2X100μg

Catalog no#

FNab01459

Price

320 EUR

Specificity

Mouse

Calculated MW

25 kDa

Uniprot ID

P07766

Form

liquid

French translation

anticorps

Tested Application

ELISA, WB, IHC

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Immunogen

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms

CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01459( CD3E Antibody) at dilution of 1:10000

Image1

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01459( CD3E Antibody) at dilution of 1:200

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.