anti- Collagen Type I antibody

Size

2X100μg

Catalog no#

FNab01836

Price

320 EUR

Form

liquid

Uniprot ID

P08123

Calculated MW

118 kDa

French translation

anticorps

Specificity

Mouse, Rat

Tested Application

ELISA, WB, IHC

Immunogen

collagen, type I, alpha 2

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene

Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )

Synonyms

Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

human kidney tissue were subjected to SDS PAGE followed by western blot with FNab01836(COL1A2 antibody) at dilution of 1:1000

Image1

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01836( COL1A2 Antibody) at dilution of 1:200

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.