Uniprot ID
P48059
Calculated MW
40 kDa
Form
liquid
French translation
anticorps
Synonyms
PINCH, PINCH1
Specificity
Human, Mouse, Rat
Tested Application
ELISA, WB, IF, IHC
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Immunogen
LIM and senescent cell antigen-like domains 1
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image1
Immunohistochemistry of paraffin-embedded human oesophagus cancer using FNab04782(LIMS1 antibody) at dilution of 1:50
Image4
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04782(LIMS1 antibody) at dilution of 1:1000
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
