Uniprot ID
Q14764
Form
liquid
Calculated MW
100 kDa
French translation
anticorps
Specificity
Human, Mouse
Tested Application
ELISA, WB, IHC, IF
Immunogen
major vault protein
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Synonyms
LRP, major vault protein, MVP, VAULT1
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image4
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab05449(MVP antibody) at dilution of 1:1000
Image1
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05449( MVP Antibody) at dilution of 1:200
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.