anti- RbAp46 antibody

Size

2X100μg

Catalog no#

FNab07147

Price

320 EUR

Specificity

Human

Uniprot ID

Q16576

Form

liquid

French translation

anticorps

Calculated MW

Refer to figures

Tested Application

ELISA, WB, IHC, IF, IP

Purification

Immunogen affinity purified

Immunogen

retinoblastoma binding protein 7

Purity

≥95% as determined by SDS-PAGE

Synonyms

Histone binding protein RBBP7, RbAp46, RBBP 7, RBBP7

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

A431 cells were subjected to SDS PAGE followed by western blot with FNab07147(RBBP7 antibody) at dilution of 1:1000

Image1

Immunohistochemistry of paraffin-embedded human cervical cancer using FNab07147(RBBP7 antibody) at dilution of 1:50

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.