Specificity
Human
Uniprot ID
Q16576
Form
liquid
French translation
anticorps
Calculated MW
Refer to figures
Tested Application
ELISA, WB, IHC, IF, IP
Purification
Immunogen affinity purified
Immunogen
retinoblastoma binding protein 7
Purity
≥95% as determined by SDS-PAGE
Synonyms
Histone binding protein RBBP7, RbAp46, RBBP 7, RBBP7
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image4
A431 cells were subjected to SDS PAGE followed by western blot with FNab07147(RBBP7 antibody) at dilution of 1:1000
Image1
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab07147(RBBP7 antibody) at dilution of 1:50
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.