Synonyms
RR1
Uniprot ID
P23921
Form
liquid
French translation
anticorps
Specificity
Human, Mouse
Tested Application
ELISA, WB, IHC
Calculated MW
Refer to figures
Purification
Immunogen affinity purified
Immunogen
ribonucleotide reductase M1
Purity
≥95% as determined by SDS-PAGE
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image4
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07492(RRM1 antibody) at dilution of 1:1000
Image1
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab07492( RRM1 Antibody) at dilution of 1:200
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.