anti- SIRT1 antibody

Size

2X100μg

Catalog no#

FNab07877

Price

320 EUR

Uniprot ID

Q96EB6

Synonyms

SIR2L1

Form

liquid

Calculated MW

130 kDa

French translation

anticorps

Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100

Immunogen

sirtuin (silent mating type information regulation 2 homolog) 1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07877( SIRT1 Antibody) at dilution of 1:1000

Image1

Immunohistochemistry of paraffin-embedded mouse testis tissue slide using FNab07877( SIRT1 Antibody) at dilution of 1:100

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.