Uniprot ID
P11387
Calculated MW
35 kDa
Form
liquid
French translation
anticorps
Specificity
Human, Mouse
Tested Application
ELISA, WB, IHC, IP
Immunogen
topoisomerase (DNA) I
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Recommended dilution
WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IP 1:50 - 1:100
Synonyms
DNA topoisomerase 1, DNA topoisomerase I, TOP1, TOPI, Top-I, topoisomerase (DNA) I
Image4
L02 cells were subjected to SDS PAGE followed by western blot with FNab08865(TOP1 antibody) at dilution of 1:1000
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image1
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab08865(TOP1 antibody) at dilution of 1:50
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.