Anti- Nuclear Factor Kappa B (NFkB) Antibody

Size

100ug

Catalog no#

GEN2008451

Price

520 EUR

Synonim names

N/A

Form/Appearance

N/A

Concentration

0.2mg/ml

French translation

anticorps

Gene synonims

Nfkb; N/A

Category

Antibodies

Clonality

Polyclonal Antibodies

Antigen

Nuclear Factor Kappa B (NFkB)

Gene name

Nuclear Factor Kappa B (NFkB) ; NFkB

Clone

Not applicable to Polyclonal Antibodies

Other names

nuclear factor kappa B; nuclear factor kappa B; N/A

Long name

Biotin-Linked Antibody to Nuclear Factor Kappa B (NFkB)

Applications

Immunohistochemistry (IHC), ELISA, EIA, IFA, ELI-Spot, Western Blot (WB)

Specificity

This is an antibody designed to detect Nuclear Factor Kappa B (NFkB) ; NFkB

Reacts with

Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Purification method

The most common purification methods used in the antibody production are Affinity Chromatography, Caprylic Acid Ammonium Sulfate Precipitation, Antigen Affinity method, etc.

Storage, shipping and handling

The antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial. We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory