Uniprot ID
P37840
Form
liquid
French translation
anticorps
Specificity
Human, Rat
Calculated MW
Refer to figures
Tested Application
ELISA, IHC, WB, IF
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Synonyms
Alpha synuclein, NACP, PARK1, PARK4, SNCA
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Immunogen
synuclein, alpha (non A4 component of amyloid precursor)
Image1
Immunohistochemistry of paraffin-embedded human brain using FNab00345(SNCA antibody) at dilution of 1:50
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Image4
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00345(SNCA antibody) at dilution of 1:1000
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
The anti- alpha-synuclein antibody is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
