anti- HNMT antibody

Size

2X100μg

Catalog no#

FNab03944

Price

320 EUR

Uniprot ID

P50135

Calculated MW

27 kDa

Form

liquid

French translation

anticorps

Specificity

Human, Mouse

Tested Application

ELISA, WB, IHC, IP

Purification

Immunogen affinity purified

Immunogen

histamine N-methyltransferase

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50

Image1

Immunohistochemistry of paraffin-embedded human lymphoma using FNab03944(HNMT antibody) at dilution of 1:50

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

human liver tissue were subjected to SDS PAGE followed by western blot with FNab03944(HNMT antibody) at dilution of 1:1000

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.