anti- NME1 antibody

Size

2X100μg

Catalog no#

FNab05762

Price

320 EUR

Uniprot ID

P15531

Calculated MW

21 kDa

Form

liquid

French translation

anticorps

Synonyms

NDPKA, NM23

Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Immunogen

non-metastatic cells 1, protein (NM23A) expressed in

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image1

Immunohistochemistry of paraffin-embedded human lung cancer using FNab05762(NME1 antibody) at dilution of 1:100

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05762(NME1 antibody) at dilution of 1:1500

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.