anti- POT1 antibody

Size

2X100μg

Catalog no#

FNab06645

Price

320 EUR

Uniprot ID

Q9NUX5

Calculated MW

75 kDa

Form

liquid

French translation

anticorps

Specificity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB, IF

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Immunogen

POT1 protection of telomeres 1 homolog (S. pombe)

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

HeLa cells were subjected to SDS PAGE followed by western blot with FNab06645(POT1 antibody) at dilution of 1:1000

Image1

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab06645(POT1 antibody) at dilution of 1:100

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.