anti- PTPN11 antibody

Size

2X100μg

Catalog no#

FNab06932

Price

320 EUR

Calculated MW

71KDa

Uniprot ID

Q06124

Form

liquid

French translation

anticorps

Synonyms

PTP2C, SHPTP2

Tested Application

ELISA, WB, IHC

Specificity

Human, Mouse, Rat

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Immunogen

protein tyrosine phosphatase, non-receptor type 11

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image4

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06932( PTPN11 Antibody) at dilution of 1:1000

Image1

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab06932( PTPN11 Antibody) at dilution of 1:50

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.