anti- SOST antibody

Size

2X100μg

Catalog no#

FNab08119

Price

320 EUR

Specificity

Human

Calculated MW

30 kDa

Uniprot ID

Q9BQB4

Form

liquid

French translation

anticorps

Immunogen

sclerosteosis

Tested Application

ELISA, WB, IHC

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Synonyms

sclerosteosis, Sclerostin, SOST, VBCH

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Image1

Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab08119( SOST Antibody) at dilution of 1:50

Image4

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08119( SOST Antibody) at dilution of 1:1000

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

Background

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.